Abstract FMS-like tyrosine kinase 3- internal tandem duplication (FLT3-ITD) remains as one of the most frequently mutated genes in acute myeloid leukemia (AML), especially in those with normal cytogenetics.The FLT3-ITD and FLT3-TKD (tyrosine kinase domain) mutations are biomarkers for high risk AML and are associated with drug resistance and high r
Abstract Background Rates of opioid prescribing tripled in the USA between 1999 and 2015 and were associated with significant increases in opioid misuse and overdose death.Roughly half of all opioids are prescribed in primary care.Although clinical guidelines describe recommended opioid prescribing practices, implementing these guidelines in a way
Background: Echinococcus granulosus cultivation is very important for improvement of different aspect of Trail Hat medical and veterinary researches.Despite many advances in this case, there is a missing link for in vitro life cycle of adult worms and it is fertili-zation.Regarding the researchers’ observations, self-fertilization can be done in
The sandfly Lutzomyia evansi from a focus of visceral leishmaniasis in northern Colombia was reared and maintained under laboratory conditions for five generations.The average time for total development was 41.8 days (range = 35.1- 49.6) at 25 oC and 89-95% of relative humidity.The mean The Sanasa Jean number of eggs laid was lower in laboratory br
Vacuum Cleaners Non-invasive tracking for monitoring the selective delivery and transplantation of biotargeted agents in vivo has been employed as one of the most effective tools in the field of nanomedicine.Different nanoprobes have been developed and applied to bioimaging tissues and the treatment of diseases ranging from inflammatory and cardiov